The singer, whose real name is Curtis Jackson, was spotted arriving at a courtroom in Van Nuys, California on Monday morning ahead of his hearing.
If convicted, the In Da Club singer faces up to five years in jail and $46,000 in fines.
Due in court: 50 Cent, shown at a party he hosted in New York City in May, is scheduled to attend a hearing today over domestic violence charges
The woman told police that during a June 23 argument, Jackson began destroying property at her Toluca Lake condo before she locked herself in a bedroom. She says Jackson kicked open the bedroom door and kicked her, causing injury.
Police estimated about $7,100 in damage to the home.
The woman told police she had been in a three-year relationship and has a baby with Jackson, who has referenced drug dealing and violence in many songs.
'Curtis Jackson denies these allegations as made against him,' his New York attorney, Scott Leemo, said after charges were filed last month.
'It is important to note, Mr. Jackson has not been arrested and there is no warrant outstanding for his arrest. (We) are currently conducting our own investigation into these allegations.'
However, City Attorney Mike Feuer said in a statement: 'Regardless of perceived celebrity or notoriety, domestic violence is a serious crime, and alleged perpetrators will be prosecuted to the fullest extent of the law by this office.'
The New York rapper is no stranger to the law, as he started dealing drugs at age 12 during the 1980s crack epidemic that hit urban America hard and left drug dealing to pursue a rap career.
He has become on of the world's highest selling rappers and founded his own record label G-Unit Records in 2003.
Jackson has starred in several films including the semi-autobiographical Get Rich or Die Tryin', which was also the name off his 2003 album.
50 Cent formerly dated talk show host Chelsea Handler and singer Ciara.